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A survey of malware behavior description and analysis Review

Bo YU, Ying FANG, Qiang YANG, Yong TANG, Liu LIU

Frontiers of Information Technology & Electronic Engineering 2018, Volume 19, Issue 5,   Pages 583-603 doi: 10.1631/FITEE.1601745

Abstract: Behavior-based malware analysis is an important technique for automatically analyzing and detecting malwarespecifications and cover the entire behavior space of the malware samples.Although there have been several works focusing on malware behavior analysis, such research is far from: malware behavior description, behavior analysis methods, and visualization techniques.First, existing behavior data types and emerging techniques for malware behavior description are explored

Keywords： Malware behavior     Static analysis     Dynamic Analysis     Behavior data expression     Behavior analysis     Machinelearning     Semantics-based analysis     Behavior visualization     Malware evolution    

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Study on Big Data-based Behavior Modification in Metro Construction

Lie-yun Ding,Sheng-yu Guo

Frontiers of Engineering Management 2015, Volume 2, Issue 2,   Pages 131-136 doi: 10.15302/J-FEM-2015037

Abstract: , construction accidents frequently happen, which are significantly attributable to workers’ unsafe behaviorBehavior-based safety (BBS) is an effective method to modify workers’ unsafe behavior.This paper introduces the study on big data-based metro construction behavior modification, aiming toFirst, the behavior modification pushing mechanism based on content-based personalized recommendationSecondly, the development of behavior modification system of metro construction (BMSMC) is introduced

Keywords： big data     unsafe behavior     behavior modification     behavior-based safety (BBS)     unsafe behavior rate    

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A hierarchical system to predict behavior of soil and cantilever sheet wall by data-driven models

Nang Duc BUI; Hieu Chi PHAN; Tiep Duc PHAM; Ashutosh Sutra DHAR

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 6,   Pages 667-684 doi: 10.1007/s11709-022-0822-4

Abstract: The uncertainty of this data-driven system is partially investigated by developing 1000 RFC models, basedon the application of random sampling technique in the data splitting process.Investigation on the distribution of the evaluation metrics reveals negative skewed data toward the 1.0000

Keywords： finite element analysis     cantilever sheet wall     machine learning     artificial neural network     random forest    

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Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Frontiers of Medicine   Pages 185-192 doi: 10.1007/s11684-020-0754-0

Abstract: Moreover, lung cells that have ACE2 expression may be the main target cells during 2019-nCoV infectionThrough scRNA-seq data analyses, we identified the organs at risk, such as lung, heart, esophagus, kidney

Keywords： 2019-nCoV     ACE2     single-cell RNA-seq    

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Discussion on the Basic Principles for Health and Medical Data Sharing

Zhang Jiannan, Li Yingying, Gu Yanju, Zhu Yelin, He Qianfeng

Strategic Study of CAE 2020, Volume 22, Issue 4,   Pages 93-100 doi: 10.15302/J-SSCAE-2020.04.012

Abstract:

Health and medical data sharing in China is in its infancy.Key issues such as privacy security, unclear data ownership, and unclear distribution of benefits havelong hindered the health and medical data sharing in China.Basic principles for the sharing can guide and promote the health and medical data sharing and help realizethe values of these data.

Keywords： data sharing，healthcare，data sharing behavior，basic principle    

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Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages

LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 166-170 doi: 10.1007/s11684-008-0030-1

Abstract: This study aims to demonstrate that blocking the receptor-interacting protein2 (Rip2) expression canRip2 small interfering RNA (siRNA) plasmids were constructed and transfected into macrophage and Rip2 expressionRip2 siRNA plasmid could block the mRNA and protein expression of Rip2 and promote cell proliferationThe HMGB1 expression in the liver decreased to (40.21 ± 11.03) pg/g, and serum TNF-?The results demonstrate that Rip2 siRNA plasmid can block the expression of Rip2, decrease the production
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MSI/LOH and extron expression of the FHIT gene in gastric carcinoma

XIAO Yuping, MAO Lili, HAN Chengbo, LI Jinyi, XU Lei, XIN Yan

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 99-103 doi: 10.1007/s11684-007-0019-1

Abstract: We detected loss of heterozygosity (LOH) and microsatellite instabilities (MSI), as well as extron expressionFour of 10 (40.0%) cases of primary GC showed absent or decreased expression of the FHIT protein as comparedThe findings in this study suggest that LOH and MSI of FHIT gene may induce aberrant extron expression
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Gene expression disparity in giant cell tumor of bone

Xiaohua PAN, Shuhua YANG, Deming XIAO, Yong DAI, Lili REN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 49-56 doi: 10.1007/s11684-009-0012-y

Abstract: The aim of this paper was to study the differential gene expression of giant cell tumor of bone (GCTBThe gene expression disparity between the GCTB samples and normal bony callus was significantly different

Keywords： giant cell tumor of bone     gene     microarray     cDNA    

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Distinct gene expression pattern of mutations coordinated by target repression and promoter hypermethylation

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 627-636 doi: 10.1007/s11684-020-0815-4

Abstract: Here, based on 1741 patients with AML, we report a unique expression pattern associated with RUNX1This expression pattern was coordinated by target repression and promoter hypermethylation.Then, based on RNA-seq data from The Cancer Genome Atlas AML cohort, we developed a 300-gene signatureThrough the integration of DNA methylation array data, we illustrated that hypermethylation on the promoterThis study revealed the distinct gene expression pattern of RUNX1 mutations and the underlying

Keywords： RUNX1     gene mutation     acute myeloid leukemia     transcriptional repression     DNA methylation    

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Immunohistochemical measurement and expression of Mcl-1 in infertile testes

Raafat Hegazy,Abdelmonem Hegazy,Mustafa Ammar,Emad Salem

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 361-367 doi: 10.1007/s11684-015-0395-x

Abstract: This study aimed to investigate the immunohistochemical expression of Mcl-1 in testicular biopsies of

Keywords： spermatogenesis     testis     Mcl-1 expression     immunohistochemical study     infertility    

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Construction of a universal recombinant expression vector that regulates the expression of human lysozyme

Shen LIU, Shengzhe SHANG, Xuezhen YANG, Huihua ZHANG, Dan LU, Ning LI

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3,   Pages 382-389 doi: 10.15302/J-FASE-2018211

Abstract: A key component in the technology is the construction of an efficient milk expression vector.Here, we established a simple method to construct a milk expression vector, by a combination of homologousThe highest expression level of rhLZ was 0.45 g·L−1, and rhLZ exhibited the sameOur results have provided a simple approach to construct a universal milk expression vector, and demonstratedthat the resulting vector regulates the expression of hLZ in milk.

Keywords： BAC recombinant methods     gene expression     human lysozyme     transgenic mice     milk expression vector    

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Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 398-400 doi: 10.1007/s11684-007-0077-4

Abstract: The aim of this paper was to investigate the relationship between the expression of adrenomedullin (ADMThe expression of ADM was detected using immunohistochemical staining in specimens from 15 normal controlsThere was a positive correlation between the ADM expression and MVD in LE and LES respectively ( = 0.823The expression of ADM in LE was statistically lower than that in LES (<0.05).mitotic figures, the higher levels of the ADM expression and poor prognosis.

Keywords： anticarcinogenic     microvessel density     malignant potency     muscle     uterine leiomyosarcoma    

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Heterologous expression of signal protein 14-3-3 in and the subsequent immune response in mice

ZHENG Meijuan, SHEN Jilong, LUO Qingli, XU Yuanhong

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 95-99 doi: 10.1007/s11684-008-0017-y

Abstract: The Sj14-3-3 gene was amplified and subcloned into the expression vector pPICZ?The recombinant Sj14-3-3 of eukaryotic expression in was successfully harvested.

Keywords： development     challenging     rSj14-3-3     resistance     cultural supernatant    

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Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 723-735 doi: 10.1007/s11684-021-0905-y

Abstract: Among them, the expression of exosomal coronin-1a (CORO1A) was 5.3-fold higher than that in the controlsoverexpressed in NSC-34 motor neuron-like cells, and apoptosis, oxidative stress, and autophagic protein expression

Keywords： amyotrophic lateral sclerosis     coronin-1a     autophagy     pathogenesis    

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Effect of arsenic trioxide on proliferation and apoptosis of U266 cells and its relationship with the expression

ZHAN Rong, YU Qinghong, HUANG Haobo

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 356-360 doi: 10.1007/s11684-008-0068-0

Abstract: trioxide (AsO) on the proliferation and apoptosis of myeloma cell line U266 and its relationship with the expressionThe effect of AsO on the VEGF expression of U266 cells were tested by enzyme linked immunosorbent assayAs far as single cells are concerned, nevertheless, the expression of VEGF mRNA did not vary.decrease the tumor load, and lead to the reduction of VEGF in the culture supernatant, but not change the expression

Keywords： VEGF expression     expression variation     culture supernatant     labeling     concentration    

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Title Author Date Type Operation

A survey of malware behavior description and analysis

Bo YU, Ying FANG, Qiang YANG, Yong TANG, Liu LIU

Journal Article

Study on Big Data-based Behavior Modification in Metro Construction

Lie-yun Ding,Sheng-yu Guo

Journal Article

A hierarchical system to predict behavior of soil and cantilever sheet wall by data-driven models

Nang Duc BUI; Hieu Chi PHAN; Tiep Duc PHAM; Ashutosh Sutra DHAR

Journal Article

Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different

Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han

Journal Article

Discussion on the Basic Principles for Health and Medical Data Sharing

Zhang Jiannan, Li Yingying, Gu Yanju, Zhu Yelin, He Qianfeng

Journal Article

Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages

LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao

Journal Article

MSI/LOH and extron expression of the FHIT gene in gastric carcinoma

XIAO Yuping, MAO Lili, HAN Chengbo, LI Jinyi, XU Lei, XIN Yan

Journal Article

Gene expression disparity in giant cell tumor of bone

Xiaohua PAN, Shuhua YANG, Deming XIAO, Yong DAI, Lili REN

Journal Article

Distinct gene expression pattern of mutations coordinated by target repression and promoter hypermethylation

Journal Article

Immunohistochemical measurement and expression of Mcl-1 in infertile testes

Raafat Hegazy,Abdelmonem Hegazy,Mustafa Ammar,Emad Salem

Journal Article

Construction of a universal recombinant expression vector that regulates the expression of human lysozyme

Shen LIU, Shengzhe SHANG, Xuezhen YANG, Huihua ZHANG, Dan LU, Ning LI

Journal Article

Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

Journal Article

Heterologous expression of signal protein 14-3-3 in and the subsequent immune response in mice

ZHENG Meijuan, SHEN Jilong, LUO Qingli, XU Yuanhong

Journal Article

Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker

Journal Article

Effect of arsenic trioxide on proliferation and apoptosis of U266 cells and its relationship with the expression

ZHAN Rong, YU Qinghong, HUANG Haobo

Journal Article